Production of PET Radionuclides

Session Organizers:
Syed M. Qaim, Forschungszentrum Juelich GmbH, Germany
Suzanne Lapi, Washington University St. Louis, Radiology, USA

While imaging with compounds labeled with the PET isotopes 18F and 11C is a relatively mature field, studies with these compounds may be limited by their relatively short half-lives (110 min and 20 min, respectively). New radionuclides (the so-called “non-standard” isotopes) are emerging as useful tools for the study of radiopharmaceuticals with longer biological half-lives such as peptides, antibodies and nanoparticles The development of novel isotopes is also paving the way for theranostic pairs, where patients may be screened with a diagnostic tracer prior to therapeutic treatment. The session(s) will provide overviews on PET isotopes and highlight the development of production routes, separation chemistry and applications for the emerging isotopes.

INVITED PAPERS

Production of longer lived positron emitters at BNL
Leonard F. Mausner, Brookhaven National Laboratory, United States

New developments in the production of generator systems
Frank Rösch, Johannes Gutenberg Universität Mainz, Institut für Kernchemie, Germany

High Power Water Targets for the Production of 18F - Review of Design Features and Analytical Techniques
Matthew Stokely, BTI Targetry LLC, United States

Production Scale Purification of Ge-68 from Irradiated Gallium Metal
Jonathan M. Fitzsimmons, Brookhaven National Laboratory, United States

Development of the Non-Standard Pet Radionuclides Ti-45, Se-73 and Br-75,76
Heinz H. Coenen, Forschungszentrum Juelich GmbH, Germany

Sustainable Production of PET Research Tracers at Wisconsin:Stayin' Alive
Jerry Nickles, Department of Medical Physics, University of Wisconsin–Madison, United States

Zirconium-89: From Production to Clinical Application
Danielle Vugts, VU University Medical Center, The Netherlands